Introduction
Human papilloma virus (HPV) infection is associated with nearly all of cervical cancer cases (95%) [1]. Identification of HPV is an important tool for screening and prevention of carcinoma of the cervix. SentisTM HPV Genotyping Testing Test combines self-sampling technology and genotyping assay to detect 14 high-risk HPVs (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68) and 3 intermediate-risk HPVs (53, 73, 82).
What clinical challenges are targeted by Sentis™ HPV Genotyping Testing
Sentis™ HPV Genotyping Testing is designed to address key challenges in cervical cancer prevention by detecting both high-risk and intermediate-risk HPV strains. By identifying these types of HPV, the test allows for early detection and intervention before precancerous changes occur, giving clinicians the opportunity to take action and prevent the progression to cancer.
In addition to screening, Sentis™ also plays a crucial role in managing abnormal Pap test results. It helps determine the presence of high-risk and intermediate-risk HPV types, guiding decisions on whether further diagnostic procedures or treatments are necessary.
Applicable Clinical Scenarios
- Women who have had sexual intercourse.
Non-applicable population
- Women who are pregnant.
- Women who have had a total hysterectomy.
- Women who have received pelvic radiation therapy.
Important features of Sentis™ HPV Genotyping Testing
| Product Name | SentisTM HPV Genotyping Testing |
| Detection Method | NGS |
| Detection Scope | 14 high-risk HPVs (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68) and 3 intermediate-risk HPVs (53, 73, 82) |
| Sample Type | Cervical Exfoliated Cells |
Why choose Sentis™ HPV Genotyping Testing
- Comprehensive Detection Technology
High-throughput sequencing technology
- Outstanding testing performance
98.82% sensitivity and 99.14% specificity
- Self-Sampling method
Convinient & Private & Storing-friendly
The Sentis™ HPV Genotyping Testing service process
Step 1
Physician orders test
Step 2
Sample collected
Step 3
Sample shipped to us and analyzed
Step 4
Results sent to physician
Localization solution of Sentis™ HPV Genotyping Testing
| Automation equipment | Sequencer | Maximum samples/ Flow cell | Sequencing time | Bioinformatics analysis |
|---|---|---|---|---|
| Manually | DNBSEQ-G99 | 768 | 12h | HPV HALOS Lite |
- User-friendly control
Independently developed desktop sequencer and automatic processing system
- Accurate detection
Patented DNB nanoball (DNB) library construction technology and Combinatorial Probe-Anchor Synthesis sequencing technology
- Flexible throughput
Metagenomic sequencing of 768 samples can be performed at a time depending on different sequencing platforms
- Comprehensive database
BGI internal database which comprehensively integrates the public variant information and BGI internal accumulated sample information
Sentis™ HPV Genotyping Testing Resources
Learn more about our product solution by downloading our relevant materials.
HPV Genotyping Testing